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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREB3L2
All Species:
21.82
Human Site:
S219
Identified Species:
53.33
UniProt:
Q70SY1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70SY1
NP_919047.2
520
57429
S219
S
D
S
E
G
S
L
S
P
N
P
R
L
H
P
Chimpanzee
Pan troglodytes
XP_001148336
520
57528
S219
S
D
S
E
G
S
L
S
P
N
P
R
L
H
P
Rhesus Macaque
Macaca mulatta
XP_001105002
372
41370
A74
E
P
S
P
T
S
P
A
P
L
I
Q
A
E
H
Dog
Lupus familis
XP_548490
393
43397
E95
S
P
R
E
A
S
V
E
H
L
H
L
P
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH52
521
57450
S219
S
D
S
E
G
S
L
S
P
N
P
R
L
H
P
Rat
Rattus norvegicus
Q6QDP7
521
57360
S219
S
D
S
E
G
S
L
S
P
N
P
R
L
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521115
314
34198
A16
I
D
D
E
V
T
E
A
Q
T
F
R
S
H
T
Chicken
Gallus gallus
XP_416356
820
89298
S516
S
D
S
E
G
G
Q
S
P
A
R
S
L
P
P
Frog
Xenopus laevis
A2VD01
525
57606
S224
S
D
S
E
G
G
Q
S
P
T
R
S
L
P
P
Zebra Danio
Brachydanio rerio
A1L224
519
56883
S216
S
D
S
E
G
S
Q
S
P
V
H
P
C
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
70.3
71.3
N.A.
90.9
90.7
N.A.
41.7
43.4
56.5
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
71.3
73.2
N.A.
94.6
93.8
N.A.
47.8
50.4
71.2
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
20
N.A.
100
100
N.A.
26.6
60
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
26.6
N.A.
100
100
N.A.
40
60
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
20
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
80
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
90
0
0
10
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
70
20
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
20
0
0
50
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
40
0
0
20
0
10
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% N
% Pro:
0
20
0
10
0
0
10
0
80
0
40
10
10
30
70
% P
% Gln:
0
0
0
0
0
0
30
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
20
50
0
0
0
% R
% Ser:
80
0
80
0
0
70
0
70
0
0
0
20
10
0
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
20
0
0
0
0
20
% T
% Val:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _